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Table 1 Effect on outcome of LPBC, CD8+, or FOXP3 tumor infiltrate by subtype

From: Clinical significance of tumor-infiltrating lymphocytes in breast cancer

 

Breast cancer subtype

TN

HR+

HER2+

Immune infiltrate

DFS or RFS

OS or DSS

DFS or RFS

OS or DSS

DFS or RFS

OS or DSS

LPBC

+++

+++

  

++

+

Elevated CD8+

+

+++

 

+

+ (TBET)

 

Elevated FOXP3

  

-

-

  
  1. Abbreviations: DFS disease free survival, RFS relapse free survival, OS overall survival, DSS disease specific survival, LPBC lymphocyte predominant breast cancer, TN triple negative, HR hormone receptor
  2. +++ Increased (>2 sources); ++ (increased 2 sources) + Increased (one source); - Decreased (one source)
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