Fig. 3

Preexisting and AE37-induced immunity to E75 and PSA₁₄₆ in HLA-A2⁺ patients. Vaccinations induced CD8⁺/E75⁺ cells in HLA-A2⁺ patients (a). Frequencies of CD8⁺/E75⁺ cells at each time point (R0, R3, R6 and LT) (b). Representative dot plots for negative control, R0 and Rmax for patient PR13 (c). Vaccinations induced CD8⁺/PSA₁₄₆ ⁺ cells in HLA-A2⁺ patients (d). Frequencies of CD8⁺/PSA₁₄₆ ⁺ cells at each time point (R0, R3, R6 and LT) (e). Representative dot plots for negative control, R0 and Rmax for patient PR6 (f)