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Fig. 4 | Journal for ImmunoTherapy of Cancer

Fig. 4

From: Sarcoidosis in the setting of combination ipilimumab and nivolumab immunotherapy: a case report & review of the literature

Fig. 4

Hematoxylin and Eosin Staining of Pre-Tibial Soft Tissue Nodule. Microscopic hematoxylin and eosin (H&E) section showing (A) large, deep dermal collections of non-caseating granulomas (a, 2×) extending into the subcutaneous tissue (b, 2×). Higher magnification shows tightly formed granulomas containing multinucleated giant cells separated by fibrous connective tissue (c, 4×). Scattered mature appearing lymphocytes are seen surrounding the granulomatous inflammation (d, 10×)

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