Fig. 1
From: Canine cancer immunotherapy studies: linking mouse and human
Efficacy of Radiation + CpG + 1MT in a Canine Clinical Trial. Canines with metastatic melanoma and sarcoma were accrued to a pilot clinical trial at the UC Davis School of Veterinary Medicine [98]. a. Baseline computed tomography of the thorax demonstrates untreated metastatic lesions in a dog with buccal melanoma. b. One month after local RT and intra-lesional CPG to the primary tumor combined with systemic indolamine-2,3 dioxygenase (IDO) inhibition, there is complete regression of some lesions and partial regression of others. Arrows denote index lesions