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Fig. 2 | Journal for ImmunoTherapy of Cancer

Fig. 2

From: Thrombocytopenia in patients with melanoma receiving immune checkpoint inhibitor therapy

Fig. 2

Bone marrow from patient with checkpoint inhibitor-induced ITP before rituximab treatment. H&E stained section of the bone marrow biopsy, 100 × magnification. The bone marrow is moderately hypercellular for age with trilineage hematopoiesis and increased megakaryocytes (black arrows) with a range of morphologies and mild clustering. These findings, coupled with the patient’s peripheral thrombocytopenia and elevated IPF, are compatible with a diagnosis of ITP

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