Fig. 1

Radiographic and hematologic responses with therapy. a Response as assessed by sequential PET scan images. Images are shown for Patients 2 and 3. The response for Patient 1 was more difficult to illustrate on PET scan as his disease was primarily confined to the bone marrow. b Serial complete blood counts during treatment with nivolumab demonstrating significant tri-lineage improvement for Patient 1. *Platelet units (×10^3/uL) are provided on the left y-axis, while hemoglobin (g/dL) and white blood cell count units (×10^3/uL) are on the right y-axis