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Fig. 7 | Journal for ImmunoTherapy of Cancer

Fig. 7

From: Gene expression markers of Tumor Infiltrating Leukocytes

Fig. 7

Application of cell scores to an immunotherapy dataset. a Total TILs score of each biopsy at each timepoint. Total TILs score was calculated as the average of all cell scores with >0.6 correlations with CD45, a metric that excluded only NK cells and neutrophils. Grey points denote non-responders; colored points denote responders. b Estimates and 95% confidence intervals for each cell score’s log2 fold-change between responders and non-responders on anti-CTLA4 (top) and anti-PD1 (bottom). c Cell scores from a single anti-CTLA4 responder before and during therapy. Scores are given as log2 fold changes from the average patient’s pre-treatment score

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