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Fig. 3 | Journal for ImmunoTherapy of Cancer

Fig. 3

From: CCR7+ selected gene-modified T cells maintain a central memory phenotype and display enhanced persistence in peripheral blood in vivo

Fig. 3

Effect of CD62L selection and timing of CCR7 selection on T cell phenotype. a CD8+ and b CD4+ T cell phenotypes following CD62L selection. Significant difference from NSC T cells is shown. c CD8+ and d CD4+ T cell phenotypes following CCR7 selection prior to, or CD62L or CCR7 selection post 14 days expansion ex vivo. Significant difference from CCR7 prior to expansion is shown. e CD8+ and f CD4+ T cell expression of additional early differentiation markers following selection prior to, or post expansion ex vivo. Error bars show ± SEM

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