Fig. 4

CART72 persistence in blood. The CC49-ζ copy number measured by quantitative PCR and expressed per 10⁶ circulating PBMCs over time is shown in: (a) Part A dose escalation phase of CART72 cells administered by IV infusion in trial C-9701; (b) Part B expansion phase of trial C-9701; and (c) CART72 cells administered by HA infusion in trial C-9702. HA, hepatic artery; PBMC, peripheral blood mononuclear cell; PCR, polymerase chain reaction