Fig. 5

Tumor trafficking of ¹¹¹In-labeled CART72 cells. ¹¹¹In-labeled CART72 cells were infused in four patients and compared to infusion of ^99mTc-MAA and imaging was performed at 3–96 hours post-infusion. Representative images from one patient at 24 hours post infusion of 10¹⁰ CART72 cells are notable for decreased penetration of ¹¹¹In-labeled CART72 cells (b) into the center of a liver metastases compared with well distributed dissemination of ^99mTc-MAA (a). ¹¹¹In, ¹¹¹Indium; ^99mTc-MAA, technetium albumin aggregated particles