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Table 1 Baseline serum and tumor TAG-72 levels from trial C-9701

From: Safety, tumor trafficking and immunogenicity of chimeric antigen receptor (CAR)-T cells specific for TAG-72 in colorectal cancer

Patient ID

Tumor TAG-72 (% positive)

Tumor TAG-72 Intensity

Serum TAG-72 (U/mL)

201A

5

2+

9.4

202B

60

2+

7.3

203C

95

2+

91.3

204D

5

1+

4.1

205E

80

2+

8.2

206K

60

2+

293.5

207L

70

2+

NA

101F

10

2+

148.3

102G

5

1+

6.4

103H

5

1+

96.9

104I

5

1+

13.6

105J

25

2+

19.8

106M

80

2+

187.4

107N

50

2+

NA

  1. NA not available
  2. Tumor TAG-72 levels were measured in archival or fresh tumors at baseline by immunohistochemistry and quantified as percentage of cells staining positive and staining intensity. Serum TAG-72 levels were measured using a CC49 capture radio-immunoassay
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