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Fig. 4 | Journal for ImmunoTherapy of Cancer

Fig. 4

From: Nuclear IRF-1 expression as a mechanism to assess “Capability” to express PD-L1 and response to PD-1 therapy in metastatic melanoma

Fig. 4

Relationship between PD-L1 and IRF-1 expression. a Correlation of IRF-1 with PD-L1 (p = 0.002). Dashed lines represent cutoffs between high and low expression cohorts for PD-L1 and IRF-1 b), c) Serial whole-tissue sections showing chromogenic IRF-1 and PD-L1 IHC staining in a patient in the IRF-1-high, PD-L1-low cohort. Scale bar = 50 uM

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