Fig. 2From: Current approaches to increase CAR T cell potency in solid tumors: targeting the tumor microenvironmentTargeting different components of the tumor microenvironment to enhance the efficacy of CAR T-cell therapy. Efforts to overcome the inhibitory effect of TME include strategies that target immunosuppressive populations (i.e. PGE2), stroma cells, cytokine networks and immune checkpoint signalsBack to article page