Table 2 Treatment Related Adverse Events occurring in > 10% of subjects OR ≥ grade 3

Fatigue

23 (65.7%)

1 (2.9%)

Nausea

20 (57.1%)

Anorexia

11 (31.4%)

Vomiting

11

1

Edema

10 (28.6%)

Anemia

8 (22.9%)

1

Diarrhea

8

Rash

8

1

Shortness of breath

7 (20%)

Constipation

5 (14.3%)

Thrombocytopenia

4 (11.4%)

Fever

1

Hypoglycemia

1