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Fig. 5 | Journal for ImmunoTherapy of Cancer

Fig. 5

From: GITR ligand fusion protein agonist enhances the tumor antigen–specific CD8 T-cell response and leads to long-lasting memory

Fig. 5

GITRL-FP effects on TC-1 tumor growth and generation of antitumor immune response in the absence of antigen-specific CD8 T cells. a TC-1 tumor–bearing mice received IP doses of GITRL-FP biweekly for 4 total doses. On day 24, untreated mice were sacrificed to examine (b) GITR expression on Tregs and (c) GITR expression on CD8 T cells. DTA-1 staining on (d) Tregs and (e) CD8 T cells following GITRL-FP treatment

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