Cerebral vasculitis mimicking intracranial metastatic progression of lung cancer during PD-1 blockade

Table 1 Results of NGS analysis from primary tumor of the patient

Genes	Amino Acid Change	Allele Ratio
ATM^a	p.Asp1853Asn	G = 0.57, A = 0.43
BRCA1	p.Asn1052Asp	T = 0.8421, C = 0.1579
BAP1	p.Arg114Cys	G = 0.8783, A = 0.1217
TSC1	p.Lys106Arg	T = 0.8925, C = 0.1075
TP53^a	p.Ala159Pro	CGCGGACGCGGGT = 0.7869, GGCGGACGCGGGT = 0.2131
MIR4673,NOTCH1^a	p.Gly347Asp	C = 0.7327, T = 0.2673
CDH1	p.Val556Leu	G = 0.9169, T = 0.0831
TP53	p.Gly266Ter	C = 0.9294, A = 0.0706, G = 0.0, T = 0.0
CDKN2A	p.Ser7fs	TC = 0.7684, T = 0.2, TT = 0.0316
MSH2	p.Ser734Phe	C = 0.9257, T = 0.0743
PTCH1	p.Gly1299Asp	C = 0.9205, T = 0.0795