Table 1 Demographic and disease characteristics
Characteristics/Variable | No. of patients (%) |
|---|---|
Age | |
Median | 61.5 |
Range | 49–81 |
Sex | |
Female | 2 (16.7) |
Male | 10 (83.3) |
ECOG (screening) | |
Grade 0 | 10 (83.3) |
Grade 1 | 2 (16.7) |
Time from diagnosis to treatment | 1.0 month (Mdn) |
Metastatic disease | 11 (91.7) |
Histologic subtypes | |
Clear cell | 11 (91.6) |
Non-clear cell (papillary) | 1 (8.4) |
Sarcomatoid features | 6 (50) |
Fuhrman nuclear grade | |
Grade 1 | 2 (16.7) |
Grade 3 | 7 (58.3) |
Grade 4 | 3 (25.0) |
< 1 year from diagnosis to targeted treatment | 11 (100) |
Karnofsky performance status <80% | 1 (9.1) |
Haemoglobin < LLN | 8 (72.7) |
Serum corrected calcium conc. > ULN | 5 (45.5) |
Lactate dehydrogenase >1.5 x ULN | 1 (9.1) |
Neutrophil count > ULN | 0 (0) |
Paltelet count > ULN | 3 (27.2) |
MSKCC prognostic group | |
Favourable | 0 (0) |
Intermediate | 5 (45.5) |
Poor | 6 (54.5) |
IMDC prognostic group | |
Favourable | 0 (0) |
Intermediate | 6 (54.5) |
Poor | 5 (45.5) |