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Table 4 Summary data for detected HLA antibodies and development of alloimmunization in patients

From: Intratumorally injected pro-inflammatory allogeneic dendritic cells as immune enhancers: a first-in-human study in unfavourable risk patients with metastatic renal cell carcinoma

Patient Dose (× 106 cells) HLA antibodies (baseline) Donor-specific HLA antibodies (Day 120)
1 5 Present No
2 5 Not present No
3 5 Not present No
4 5 Not present Yes (Anti-DR4)
5 10 Not present No
6 10 Present No
7 10 Present (Anti-A2) Yes (Anti-A2)
8 10 Not present Yes (Anti-B44)
9 10 Present Yes (Anti-A24,B44)
10 20 Present Not done
11 20 Not present No
12 20 Present No