Skip to main content

Table 4 Summary data for detected HLA antibodies and development of alloimmunization in patients

From: Intratumorally injected pro-inflammatory allogeneic dendritic cells as immune enhancers: a first-in-human study in unfavourable risk patients with metastatic renal cell carcinoma

Patient

Dose (× 106 cells)

HLA antibodies (baseline)

Donor-specific HLA antibodies (Day 120)

1

5

Present

No

2

5

Not present

No

3

5

Not present

No

4

5

Not present

Yes (Anti-DR4)

5

10

Not present

No

6

10

Present

No

7

10

Present (Anti-A2)

Yes (Anti-A2)

8

10

Not present

Yes (Anti-B44)

9

10

Present

Yes (Anti-A24,B44)

10

20

Present

Not done

11

20

Not present

No

12

20

Present

No