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Fig. 3 | Journal for ImmunoTherapy of Cancer

Fig. 3

From: Pretreatment antigen-specific immunity and regulation - association with subsequent immune response to anti-tumor DNA vaccination

Fig. 3

Differences in peripheral blood cellular subsets were not detected in immune responding and non-responding patients. The percentage of T cells (CD3 + CD4+ T cells or CD3 + CD8+ T cells), B cells (CD3-CD19+), monocytes (CD14+), (Panel a); NK cells (CD56 + CD3-), NK T cells (CD56 + CD3+), (Panel b); dendritic cells (HLADR + CD11c + CD14-), (Panel c); and MDSCs (CD3-HLA-DRlow/negCD33 + CD11b + CD14+) and T regulatory cells (CD3 + CD4 + CD127-CD25 + FoxP3+) (Panel d) was evaluated in PBMCs from immune responding and non-responding patients. Each dot represents the percentage of each cell type among total live PBMCs from an individual subject (closed squares, immune-responders (n = 7); open squares, non-responders (n = 22)). Lines represent median values for each data set. Samples were analyzed in duplicate and averaged. Cryopreserved samples were not available for this analysis for 9 subjects

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