Fig. 1
a. Schematic of experiment. Starting on day 12 of tumor growth, TC-1 tumor-bearing, 6–8-week-old C57BL/6 female mice (n = 10 per group) were given anti-GITR Ab (i.p., 5 mg/kg daily, total 4 doses) along with Listeria-based E7 vaccine (i.p., two doses) every 7 days. Tumor growth and survival were measured until the end of the experiment. b. Tumor growth for individual mice in each group is presented. The number of mice with completely regressed tumors out of the 10 mice in the group is indicated. c. Averaged tumor volumes following various treatments. Statistical significance is shown for day 24. d. Kaplan-Meier plot for survival. e. SK Plot showing the tumor volume and survival for each mouse at different days. (*P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001, ****P ≤ 0.0001)