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Fig. 3 | Journal for ImmunoTherapy of Cancer

Fig. 3

From: Genetic engineering of human NK cells to express CXCR2 improves migration to renal cell carcinoma

Fig. 3

Adhesion of NK cells incorporating the transgenes. a Flow cytometry analysis of CD11a (n = 6) and CD11b (n = 4) expression on NK cells incorporating (CXCR2+ and NGFR+) and not incorporating the respective transgene (CXCR2- and NGFR-). b Representative dot plots depicting counts of collected events within the double-positive gate after 0-min and 10-min co-cultures of CFSE-labeled K562 cells and BMQC-labeled NK cells. c NK cells incorporating and not incorporating the CXCR2 (n = 5) or NGFR (n = 6) transgenes in conjugates with K562 cells after 10 min of co-culture. d Degranulation against K562 of CXCR2- and CXCR2+ NK cells, as assessed by flow cytometry (n = 4)

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