Fig. 3From: Melanoma brain metastases treated with stereotactic radiosurgery and concurrent pembrolizumab display marked regression; efficacy and safety of combined treatmentUntreated lesion response after SRS and pembrolizumab. In a patient who underwent SRS to a right cerebellar melanoma brain metastasis, a CR in an untreated right frontal lesion was observed. The right frontal lesion was not initially treated, as it was not clearly pathologic on pre-SRS scan. In an unplanned MRI 12 days post-SRS, the untreated lesion is more convincing of a metastasis. On planned follow-up MRI, both treated and untreated lesion display a CRBack to article page