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Table 2 Adverse events in patients receiving RT plus pembrolizumab (n = 21)

From: Melanoma brain metastases treated with stereotactic radiosurgery and concurrent pembrolizumab display marked regression; efficacy and safety of combined treatment

Adverse Event

Grade 1

Grade 2

Grade 3

Grade 4

Diarrhea/nausea

3

   

Pruritis/Rash

2

1

  

Cardiopulmonary

Hepatitis

 Fatigue

14

   

 Headache

2

   

 CNS bleeding

 

1

  

(from treated BM)

 Seizure

1

1

  

 Cognitive change

2

1

  

 Neurologic dysfunction

1

1

  

 Perilesional Edema

 

3

1

 
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