Fig. 2From: Immuno-thermal ablations – boosting the anticancer immune response a Ablation therapy alone is often sufficient to activate the immune system; however, the CTLA-4 and PD-1 checkpoints regulate and inhibit the induction of a more robust immune response [2, 3, 7, 12, 13]. B - Both anti -PD-1 and anti-CTLA-4 antibodies enhance the immune response induced via ablation monotherapy by blocking regulatory checkpoints. [2, 3, 7, 12,13,14, 35, 54]Back to article page