Skip to main content

Table 1 Breast cancer related peptides employed in the 9 peptide vaccine and the tetanus peptide adjuvant

From: A pilot study of the immunogenicity of a 9-peptide breast cancer vaccine plus poly-ICLC in early stage breast cancer

Allele Sequence Epitope
HLA-A1 EADPTGHSY MAGE-A1 161–169
  EVDPIGHLY MAGE-A3 168–176
HLA-A2 KIFGSLAFL Her-2/neu 369–377
  YLSGADLNL CEA 571–579*
  GLYDGMEHL MAGE-A10 254–262
HLA-A3 HLFGYSWYK CEA 27–35
  VLRENTSPK Her-2/neu 754–762
  SLFRAVITK MAGE-A1 96–104
HLA-A3/HLA-A31 ASGPGGGAPR NY-ESO-1 53–62
Tetanus toxoid-derived helper peptide
Binds to multiple class II alleles AQYIKANSKFIGITEL p2830–844**
  1. *Asparagine to aspartic acid change at position 576
  2. **An alanine residue was added to the N-terminus to prevent cyclization