Safety in treatment of hepatocellular carcinoma with immune checkpoint inhibitors as compared to melanoma and non-small cell lung cancer

Table 2 Total adverse events reported per cancer

Disease	Number of Patients	Taken off therapy secondary to toxicity	Death secondary to toxicity	Elevation AST any grade	Elevation AST grade 3–4	Elevation ALT any grade	Elevation ALT grade 3–4	Diarrhea any grade	Diarrhea grade 3–4
HCC	314	16	0	51	30	41	16	40	4
NSCLC	1866	75	10	43	6	47	5	161	22
Melanoma	4118	548	21	156	33	179	38	1242	320

HCC Hepatocellular Carcinoma, NSCLC Non-small cell lung cancer, AST aspartate aminotransferase, ALT alanine aminotransferase