Patient | Age (years) | Total NK Cells Injected (× 106) | Toxicity | Status | Survival Time (months) | Cause of Deatha | 6-Month Metastasis-Free Survivalb |
---|---|---|---|---|---|---|---|
1 | 14.8 | 30.3 | Â | Dead | 2.4 | Metastases | No |
2 | 9.1 | 25.34 | Infection at injection site | Alive | 8.1 | n/a | Yes |
3 | 9.1 | 547 | Â | Alive | 11.2 | n/a | Yesc |
4 | 5.8 | 254.33 | Â | Alive | 6.0 | n/a | Yes |
5 | 1.2 | 102.63 | Grade 3 fever/chills/dehydration attributed to rhIL-2 reaction; Infection at injection site requiring surgery | Dead | 8.1 | Metastases | Yes |
6 | 6.3 | 216.4 | Infection at injection site requiring surgery | Dead | 4.1 | Perforated ulcer | No |
7 | 7.5 | 234 | Â | Dead | 2.9 | Pathologic fracture/ metastases | No |
8 | 5.0 | 305 | Â | Dead | 1.6 | Pathologic fracture | No |
9 | 8.9 | 355 | Â | Alive | 7.6 | n/a | Yes |
10 | 10.2 | 132 | Â | Dead | 5.0 | Metastases | No |