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Table 3 Non-hematologic Toxicities

From: A pilot study of an autologous tumor-derived autophagosome vaccine with docetaxel in patients with stage IV non-small cell lung cancer

Toxicity Grade 1
N (%)
Grade 2
N (%)
Grade 3
N (%)
Grade 4
N (%)
Grade 5
N (%)
Dyspnea   2 (33.3%) 2 (33.3%) 1 (16.7%)  
Respiratory Failure     1 (16.7%) 1 (16.7%)
Upper Respiratory Infection   1 (16.7%)    
Cough   1 (16.7%) 1 (16.7%)   
Pneumonia     1 (16.7%)  
Hallucinations    1 (16.7%)   
Dehydration 1 (16.7%)   1 (16.7%)   
Hypotension   1 (16.7%) 1 (16.7%)   
Dermatology, Other (Heating pad burn) 1 (16.7%)     
Pain   1 (16.7%) 1 (16.7%) 1 (16.7%)  
Peripheral Neuropathy 1 (16.7%)     
Hyperglycemia 1 (16.7%)     
Infection   1 (16.7%)    
Sore throat 1 (16.7%)     
Flu-like symptoms 1 (16.7%)     
Fatigue 1 (16.7%) 4 (66.7%)    
Arthralgia 1 (16.7%)     
Headache 1 (16.7%)     
Fever 2 (33.3%)     
Decreased level of consciousness    1 (16.7%)   
Nausea/Vomiting 1 (16.7%)     
Hyponatremia     1 (16.7%)  
Hypoxia    1 (16.7%)   
Syncope    1 (16.7%)   
Rash 1 (16.7%)     
Injection site reactiona 1 (16.7%)     
Infection, Other (Lip)b   1 (16.7%)    
Dizziness 1 (16.7%)     
Constipation 1 (16.7%)     
Hypoalbuminemia   1 (16.7%)    
  1. aAttributed to DRibble vaccine
  2. bAttributed as unlikely related to DRibble vaccine
  3. All other toxicities were attributed as unrelated to DRibble vaccine, but were considered related to docetaxel or underlying disease