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Table 2 Timing of Immune-Related Adverse Events with Relation to IL-2 Treatment

From: Improved survival and tumor control with Interleukin-2 is associated with the development of immune-related adverse events: data from the PROCLAIMSM registry

 

irAEs/Total Patients (%)

Prior to IL-2

During IL-2

After IL-2

Total

152/1535 (8.4%)

31

24

97

mM

99/623 (16%)

16

12

71

mRCC

53/920 (5.8%)

15

12

26

Total irAEs

 

31

24

97

Related to IL-2

 

NA

During and after IL-2

74

Undetermined if Related to IL2 or CPI

 

NA

 

15

Related to CPI

 

NA

 

24

  1. mM metastatic melanoma, mRCC metastatic renal cell cancer, irAEs immune-related adverse events, IL-2 interleukin-2, CPI checkpoint inhibitor, NA - not applicable