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Table 1 Tumor model main parameters and associated values

From: Mathematical modeling of tumor-associated macrophage interactions with the cancer microenvironment

Parameter

Value

Reference

Tumor tissue threshold for hypoxia

0.5750

Calibrated to match [11]

Tumor tissue threshold for necrosis

0.5325

Calibrated to match [11]

Oxygen diffusivity

1 (*)

[39]

Oxygen transfer rate from vasculature

5 (*)

[39]

Oxygen uptake rate by proliferating tumor cells

1.5 (*)

[39]

Oxygen uptake rate by hypoxic tumor cells

1.3 (*)

[39]

Oxygen uptake rate by tumor microenvironment

0.12 (*)

[39]

Oxygen decay rate

0.35 (*)

[39]

  1. (*) Value is non-dimensionalized by the diffusivity of oxygen [68] (1 × 10−5 cm2 s−1)