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Table 1 Neuro-oncology evaluation

From: Inflammatory demyelinating polyneuropathy versus leptomeningeal disease following Ipilimumab

Laboratory test Value Normal Units
Blood
 TSH 2.11 0.55–4.78 mcIU/mL
 CK 91 49–397 Unit/L
 WBC 11.7 4.2–9.1 K/uL
 Vitamin B12 587 211–911 Pg/mL
CSF
 Initial
  WBC 1 0–5 Cells/uL
  RBC 0 0 Cells/uL
  Protein > 300 15–45 Mg/dL
  Glucose 73 40–70 Mg/dL
  Cytology Negative for malignant cells   
 6 month Follow-up
  WBC 3 0–5 Cells/uL
  RBC 6 0 Cells/uL
  Protein 169 15–45 Mg/dL
  Glucose 56 40–70 Mg/dL
  Cytology atypical cells with hyperchromatic nuclei and pigmentation, suspicious for melanoma   
 Autoimmune Studies
  Asialo-GM1 (IgG/IgM) 13 0–50 IV
  GM2 (IgG/IgM) 4 0–50 IV
  GD1a (IgG/IgM) 8 0–50 IV
  GD1b (IgG/IgM) 4 0–50 IV
  GQ1b (IgG/IgM) 5 0–50 IV
  GM-1 (IgG) 3 0–50 IV
  GM-1 (IgM) 5 0–50 IV
  AMA 1.5 0–20 Units
  Rheumatoid Factor <  20 <  20 IU/mL
  ANCA <  1:20 <  1:20  
  dsDNA antibody Negative   
  ENA Negative   
  Borrelia burgdorferi antibody 0.20 0–1.20 LIV
  Leishmania antibody IgG 0 0 units
 Hepatitis panel
  Hepatitis B surface antigen Negative   
  Hepatitis B surface antibody 0.04a   mIU/mL
  Hepatitis B core antibody Negative   
  Hepatitis C antibody Negative   
 Viral studies
  CMV antibody Positive   
  EBV nuclear antigen Positive   
  EBV viral capsid antigen IgG Positive   
  EBV viral capsid antigen IgM Negative   
  HIV Negative   
  Herpes 1 IgG Negative   
  Herpes 2 IgG Negative   
  1. Abbreviations: TSH thyroid stimulating hormone, CK creatinine kinase, WBC white blood cell, RBC red blood cell, GM monosialoganglioside, GD disialoganglioside, GQ tetrasialoganglioside, ENA extractable nuclear antigen screen, ANCA anti-neutrophil cytoplasmic antibody, dsDNA double stranded DNA, AMA Mitochondrial M2 antibody IgG, CMV Cytomegalovirus, EBV Epstein-Barr virus, HIV human immunodeficiency virus, IV index value, LIV Lyme index value
  2. aHepatitis B surface antibody < 8 mIU/mL indicates inadequate antibody response to vaccination