Fig. 4

Mechanistic differences between animals with progressing tumor growth (‘non-responders’, orange color) vs. animals with full efficacy (tumor rejection – ‘responders’, green color). a Distribution of individual S L parameter values. b Maximal DC m levels. c Maximal counts of intra-tumoral dT eff cells. d Intra-tumoral nT eff cells before treatment start. e Intra-tumoral dT eff cells before treatment start. Grey dots: individual parameter values or model simulations, respectively