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Fig. 4 | Journal for ImmunoTherapy of Cancer

Fig. 4

From: Radiation and PD-(L)1 treatment combinations: immune response and dose optimization via a predictive systems model

Fig. 4

Mechanistic differences between animals with progressing tumor growth (‘non-responders’, orange color) vs. animals with full efficacy (tumor rejection – ‘responders’, green color). a Distribution of individual S L parameter values. b Maximal DC m levels. c Maximal counts of intra-tumoral dT eff cells. d Intra-tumoral nT eff cells before treatment start. e Intra-tumoral dT eff cells before treatment start. Grey dots: individual parameter values or model simulations, respectively

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