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Fig. 3 | Journal for ImmunoTherapy of Cancer

Fig. 3

From: Prime-boost vaccination targeting prostatic acid phosphatase (PAP) in patients with metastatic castration-resistant prostate cancer (mCRPC) using Sipuleucel-T and a DNA vaccine

Fig. 3

Sipuleucel-T and DNA immunization elicit PAP-specific antibody responses. a Shown are results for indirect ELISA evaluating IgG responses to PAP for two individuals (ID010 (right) and ID015 (left)) at each time point at different sera dilutions. ΔO.D. represents the difference in optical density at each serum concentration for PAP relative to blank well. b Shown are IgG antibody titers to PAP, GM-CSF, PSA, and tetanus toxoid (TET) for all patients at each time point. Blue symbols represent patients treated in Arm 1, red symbols represent patients treated in Arm 2. Bars show the mean and standard error for each group

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