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Table 1 Patient Characteristics and Response Rates

From: Talimogene Laherparepvec combined with anti-PD-1 based immunotherapy for unresectable stage III-IV melanoma: a case series

Consecutive Patients (n = 10)

Sex

Male = 7, Female = 3

Median Age (range)

70 (52–82)

Follow-up Time

4.5–13.6 Months

ECOG Performance Score

0 = 5, 1 = 4, 2 = 1

Patients with Distant Metastases

2

Unresectale Stage III

8

Stage IV

2

Prior exposure to immunotherapy

(1 adjuvant therapy, 2 systemic therapies)

Prior exposure to targeted therapy

1

Overall Response Rate (On-target lesions)

9/10

Overall Response Rate(Off-target lesions)

2/2