Fig. 4

Mixed leukocyte reaction. An allogenic mixture of 5 × 10³ human monocyte-derived immature dendritic cells and 1 × 10⁵ negatively selected CD3⁺ T cells were incubated with various concentrations of sv6D. a Effect of concentration of sv6D in the medium on release of IFN-γ after 5 days of culture. The figure shows results from an experiment with 3 replicates analyzed by one-way ANOVA, which at 10 nM sv6D, ρ = 0.0064. b The time course of the appearance of IFN-γ in the medium of cultures incubated with 10 nM sv6D in (a)