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Table 2 Performance Characteristics of MSIplus, Large-Panel NGS, and MSI-PCR in Prostate Cancer

From: Microsatellite instability in prostate cancer by PCR or next-generation sequencing

Assay

Sensitivity [95% CI]

Specificity [95% CI]

MSIplus

96.6% [80.4%–99.8%]

100% [92.7%–100%]

Large-Panel NGS

93.1% [75.8%–98.8%]

98.4% [90.2%–99.9%]

MSI-PCR

72.4% [52.5%–86.6%]

100% [92.7%–100%]