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Fig. 1 | Journal for ImmunoTherapy of Cancer

Fig. 1

From: Cytokine release syndrome

Fig. 1

Clinical presentation of CRS. Beginning with fever and unspecific symptoms CRS might impact most organ systems. Mild cases can present as flu-like illness. Grade °III to IV shows signs of life threatening cardiovascular, pulmonary and renal involvement. Neurotoxicity can occur concurrent or with delay. Abbreviations: DIC: disseminated intravascular coagulation; INR: international normalized ratio; PTT: partial thromboplastin time

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