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Table 3 Association of cancer stage and irAE in patients with melanoma or solid tumor

From: Immune-checkpoint inhibitor-induced diarrhea and colitis in patients with advanced malignancies: retrospective review at MD Anderson

  Cancer stage III
n = 25
Cancer stage IV
n = 232
P
Diarrhea/colitisa 18 (72.0) 82 (35.3) 0.001
IrAE immunosuppressant treatmentb    
Steroid alone 4 (16.0) 38 (16.4) 1.000
Steroid/Infliximab 12 (48.0) 23 (9.9) < 0.001
Mean length of steroid treatment (days, SD) 59 (33) 59 (85) 0.962
  1. Abbreviations: irAE, ICPI related adverse event; SD, standard deviation
  2. aTotal 17 patients with diarrhea/colitis had missing staging information
  3. bImmunosuppressant treatment was administrated in total 77 patients