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Table 3 Association of cancer stage and irAE in patients with melanoma or solid tumor

From: Immune-checkpoint inhibitor-induced diarrhea and colitis in patients with advanced malignancies: retrospective review at MD Anderson

 

Cancer stage III

n = 25

Cancer stage IV

n = 232

P

Diarrhea/colitisa

18 (72.0)

82 (35.3)

0.001

IrAE immunosuppressant treatmentb

   

Steroid alone

4 (16.0)

38 (16.4)

1.000

Steroid/Infliximab

12 (48.0)

23 (9.9)

< 0.001

Mean length of steroid treatment (days, SD)

59 (33)

59 (85)

0.962

  1. Abbreviations: irAE, ICPI related adverse event; SD, standard deviation
  2. aTotal 17 patients with diarrhea/colitis had missing staging information
  3. bImmunosuppressant treatment was administrated in total 77 patients