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Table 4 Multivariate logistic regression for colitis risk

From: Immune-checkpoint inhibitor-induced diarrhea and colitis in patients with advanced malignancies: retrospective review at MD Anderson

 

IrAEa

Characteristic

OR (95% CI)

P

Race (Caucasian)

5.76 (2.03–16.36)

0.001

Cancer stage IV

0.09 (0.03–0.30)

< 0.001

Cancer type (Melanoma)

1.96 (1.04–3.67)

0.037

ICPI agent

  

 Ipilimumab + combination

2.23 (1.03–4.81)

0.041

 Nivolumab

0.39 (0.14–1.11)

0.079

Duration of ICPI treatment

0.99 (0.99–1.00)

0.049

  1. aRace, cancer stage, cancer type, ICPI agent, and duration of ICPI treatment were included in the multivariate logistic regression for colitis risk