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Fig. 2 | Journal for ImmunoTherapy of Cancer

Fig. 2

From: In-field and abscopal response after short-course radiation therapy in patients with metastatic Merkel cell carcinoma progressing on PD-1 checkpoint blockade: a case series

Fig. 2

Case B. FDG-avid adenopathy before and after RT with target volume outlined in red and untreated disease outlined in blue. Left (Panel a): Coronal pre-RT PET/CT demonstrating mediastinal FDG-avid adenopathy in the mediastinum and bilateral hila (top) and upper abdomen (bottom); not pictured: supraclavicular adenopathy. Right (Panel b): Coronal PET/CT at 12 months after RT demonstrating radiographic response in the mediastinum and bilateral hila (top) and radiographic response in the upper abdomen (bottom). Panel c: Timeline of therapy and disease status, with A and B corresponding to time points depicted in Panel a and b above. c1 = cycle 1 of pembrolizumab. RT = radiation therapy. PET/CT = positron emission tomography/computed tomography. FDG = fludeoxyglucose

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