Fig. 4
From: Near complete response to Pembrolizumab in microsatellite-stable metastatic sebaceous carcinoma
Peripheral blood mononuclear cell (PBMC) phenotyping at 6-month (24 week) follow-up visit. a Dot plots show lymphocyte gating and the relative frequency of CD3-CD56+ NK cells and CD3+ T cells. b Dot plots show relative frequency of CD4 + CD45RA- memory T cells expressing CCR7 and CD27, and CD127lo CD25+ regulatory T cells. c Dot plots of CD3 + CD8+ gated cells show that CD45RA-CD8+ T cells stain for memory markers CCR7 and CD27, and there are smaller populations of CD45RA + CCR7- and CD45RA + CD27- effector T cells. d NK cells are mature (CD56 dim), terminally differentiated (CD57+) and express the Fc-gamma receptor, CD16. Numbers inside dot plots indicate the percentage of cells for the markers analyzed