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Fig. 5 | Journal for ImmunoTherapy of Cancer

Fig. 5

From: Co-transfer of tumor-specific effector and memory CD8+ T cells enhances the efficacy of adoptive melanoma immunotherapy in a mouse model

Fig. 5

Tmem and Teff have different temporal patterns of melanoma inhibition in vitro. Teff and Tmem were co-cultured with B16GP33 melanoma cells in the presence of 10 ng/mL recombinant human IL-2 for 72 h. Control wells contained no T cells. Serial MTT assays were performed every 6 h. Over approximately the first 8 h, Teff produced significantly greater inhibition of B16GP33. At all later time points, Tmem demonstrated significantly greater suppression of tumor growth. This experiment was repeated twice with similar results, 3 samples per group. († p < 0.05 compared with Teff)

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