TIS Biology | Gene | Protein | Function |
---|---|---|---|
Antigen Presenting Cell Abundance | PSMB10 | PSB10 | Immunoproteosome Subunit |
HLA-DQA1 | MHC class II DQA1 | MHC Class II Antigen Presentation | |
HLA-DRB1 | MHC class II DRB1 | MHC Class II Antigen Presentation | |
CMKLR1 | CML1 | Chemokine Receptor | |
T Cell/ NK Cell Abundance | HLA-E | HLAE | Nonclassical Class I Antigen Presentation |
NKG7 | NKG7 | Cytolytic Granule Protein | |
CD8A | CD8A | MHC Class I Coreceptor | |
IFN Activity | CCL5 | CCL5 | Monocytes and Memory T cells Chemoattractant |
CXCL9 | CXCL9 | Lymphocyte Chemoattractant | |
CD27 | CD27 | Lymphocyte Activation | |
CXCR6 | CXCR6 | T cell Activation | |
IDO1 | IDO | Inhibitor of T cell Proliferation and Function | |
STAT1 | STAT1 | Transcription Factor Mediating IFN Response | |
T Cell Exhaustion | TIGIT | TIGIT | Inhibitor of T cell Function |
LAG3 | LAG3 | Inhibitor of T cell Function | |
CD274 | PD-L1 | Inhibitor of T cell Function | |
PDCD1LG2 | PD-L2 | Inhibitor of T cell Function | |
CD276 | B7-H3 | Inhibitor of T cell Function |