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Fig. 3 | Journal for ImmunoTherapy of Cancer

Fig. 3

From: Dexamethasone-induced immunosuppression: mechanisms and implications for immunotherapy

Fig. 3

Naïve and effector memory T cells show sensitivity to dexamethasone. a Healthy donor T cells were sorted into TN, TCM, and TEM subsets by flow cytometry. Sorted subsets were cultured with αCD3/CD80 microbeads in the presence of dexamethasone (red) or vehicle control (black). Total cell numbers, Precursor Frequency, Expansion Index, and Proliferation Index of CD4 T cells (top) and CD8 T cells (bottom) are shown. All samples were plated in duplicate and analyzed with a paired, two-tailed T test. Data are representative of three independent experiments

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