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Table 2 Overall and Progression Free Survival (All patients)

From: Efficacy of metformin in combination with immune checkpoint inhibitors (anti-PD-1/anti-CTLA-4) in metastatic malignant melanoma

Cohort A (No Metformin)

Cohort B (Metformin)

Overall Survival

 • 67.7% patients alive at 1 year

• 88.2% patients alive at 1 year

 • 62.0% patients alive at 2 years

• 73.3% patients alive at 2 years

 • 20.7% patients alive at 3 years

• 73.3% patients alive at 3 years

Progression Free Survival

 • 36.6% patients free from progression at 1 year

• 56.1% patients free from progression at 1 year

 • 31.3% patients free from progression at 2 years

• 49.1% patients free from progression at 2 years