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Table 3 Overall and Progression free survival in Patients receiving only PD-1 therapy

From: Efficacy of metformin in combination with immune checkpoint inhibitors (anti-PD-1/anti-CTLA-4) in metastatic malignant melanoma

Cohort A (No Metformin)

Cohort B (Metformin)

Overall Survival

 • 64.6% patients alive at 1 year

• 100% patients alive at 1 year

 • 55.4% patients alive at 2 years

• 72.9% patients alive at 2 years

Progression Free Survival

 • 36.3% patients free from progression at 1 year

• 59.6% patients free from progression at 1 year

 • 27.2% patients free from progression at 2 years

• 47.6% patients free from progression at 2 years