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Fig. 1 | Journal for ImmunoTherapy of Cancer

Fig. 1

From: A team effort: natural killer cells on the first leg of the tumor immunity relay race

Fig. 1

The tumor-immune relay race. Natural Killer (NK) cells are the first to arrive in the tumor microenvironment and recruit CD103+ dendritic cells (DC) through the secretion of chemokines. Activated DC then transport antigen from the tumor to the tumor-draining lymph node where they prime T cells (T). DC residence in tumors is also critical to drive effector T cell recruitment into the tumor microenvironment. Sensing and eradication of tumors is thus the result of collaboration of distinct cell types within the tumor microenvironment

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