Table 1 Examples of recent trials for non-replicating-virus-mediated cancer gene therapy
From: White paper on microbial anti-cancer therapy and prevention
Biological Agent | Virus (gene) | NCT# | Indication |
|---|---|---|---|
AAV2hAQP1 | AAV (Aquaporin-1) | NCT02446249 | Squamous cell Head and Neck cancer |
NP2 | HSV-1 (NP2) | NCT00804076 | Cancer pain |
Ad5CMV-p53 | Adenovirus (p53) | NCT00003147 | Liver cancer |
TK99UN | Adenovirus (HSV TK) | NCT00844623 | Hepatocellular carcinoma |