Table 2 Examples of active studies with oncolytic viruses
From: White paper on microbial anti-cancer therapy and prevention
| Biological Agent | Virus | NCT# | Indication |
|---|---|---|---|
| TG6002 | Vaccinia virus | NCT03294486 | Glioblastoma |
| ADV/HSV-tk | Adenovirus | NCT03004183 | NSCLC and triple-negative Breast Cancer |
| Pexa-Vec | Vaccinia |
NCT03206073 NCT02562755 |
Colorectal Hepatocellular Carcinoma |
| LOAd703 | Adenovirus | NCT02705196 | Pancreatic Cancer |
| CG0070 | Adenovirus | NCT02365818 | Bladder cancer |
| MV-NIS | Measles |
NCT00408590 NCT02192775 |
Ovarian cancer Multiple myeloma |
| HF-10 | HSV-1 | NCT03252808 | Melanoma |
| GL-ONC1 | Vaccinia virus |
NCT02714374 NCT02759588 |
Solid Tumors Ovarian cancer |
| VCN-01 | Adenovirus | NCT02045602 | Advanced Solid Tumors |
| Ad-MAGEA3 | Adenovirus | NCT02879760 | NSCLC |
| OBP-301 | Adenovirus | NCT03190824 | Unresectable Metastatic Melanoma |
| G207 | HSV-1 | NCT02457845 | Pediatric Brain Tumors |