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Table 2 Examples of active studies with oncolytic viruses

From: White paper on microbial anti-cancer therapy and prevention

Biological Agent

Virus

NCT#

Indication

TG6002

Vaccinia virus

NCT03294486

Glioblastoma

ADV/HSV-tk

Adenovirus

NCT03004183

NSCLC and triple-negative Breast Cancer

Pexa-Vec

Vaccinia

NCT03206073

NCT02562755

Colorectal

Hepatocellular Carcinoma

LOAd703

Adenovirus

NCT02705196

Pancreatic Cancer

CG0070

Adenovirus

NCT02365818

Bladder cancer

MV-NIS

Measles

NCT00408590

NCT02192775

Ovarian cancer

Multiple myeloma

HF-10

HSV-1

NCT03252808

Melanoma

GL-ONC1

Vaccinia virus

NCT02714374

NCT02759588

Solid Tumors

Ovarian cancer

VCN-01

Adenovirus

NCT02045602

Advanced Solid Tumors

Ad-MAGEA3

Adenovirus

NCT02879760

NSCLC

OBP-301

Adenovirus

NCT03190824

Unresectable Metastatic Melanoma

G207

HSV-1

NCT02457845

Pediatric Brain Tumors

  1. Abbreviations: NSCLC non-small cell lung cancer