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Table 2 Examples of active studies with oncolytic viruses

From: White paper on microbial anti-cancer therapy and prevention

Biological Agent Virus NCT# Indication
TG6002 Vaccinia virus NCT03294486 Glioblastoma
ADV/HSV-tk Adenovirus NCT03004183 NSCLC and triple-negative Breast Cancer
Pexa-Vec Vaccinia NCT03206073
NCT02562755
Colorectal
Hepatocellular Carcinoma
LOAd703 Adenovirus NCT02705196 Pancreatic Cancer
CG0070 Adenovirus NCT02365818 Bladder cancer
MV-NIS Measles NCT00408590
NCT02192775
Ovarian cancer
Multiple myeloma
HF-10 HSV-1 NCT03252808 Melanoma
GL-ONC1 Vaccinia virus NCT02714374
NCT02759588
Solid Tumors
Ovarian cancer
VCN-01 Adenovirus NCT02045602 Advanced Solid Tumors
Ad-MAGEA3 Adenovirus NCT02879760 NSCLC
OBP-301 Adenovirus NCT03190824 Unresectable Metastatic Melanoma
G207 HSV-1 NCT02457845 Pediatric Brain Tumors
  1. Abbreviations: NSCLC non-small cell lung cancer