Table 4 Examples of active clinical studies with bacteria
From: White paper on microbial anti-cancer therapy and prevention
Biological Agent | Bacterium | NCT# | Indication |
|---|---|---|---|
IL-2 | Salmonella | NCT01099631 | Liver Cancer |
C. novyi-NT | Clostridium | NCT00358397 NCT01118819 NCT01924689 | Solid Tumors |
APS001F | Bifidobacterium | NCT01562626 | Solid Tumors |
JNJ-64041757 | Listeria | NCT02592967 NCT02625857 | NSCLC Prostate Cancer |
JNJ-757 | Listeria | NCT03371381 | Lung Cancer |
pLADD | Listeria | NCT03189030 | Metastatic Colorectal Cancer |
ADU-623 | Listeria | NCT01967758 | Astrocytic Tumors |
ADXS11-001 | Listeria | NCT01598792 NCT01266460 | Oropharyngeal Cancer Cervical Cancer |
CRS-207 | Listeria | NCT01675765 NCT00585845 NCT02575807 | Malignant Pleural Mesothelioma Adenocarcinoma of the Pancreas Ovarian Cancer |
GVAX & CRS-207 | Listeria/GVAX | NCT02004262 | Pancreatic Cancer |